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Monday, April 25, 2016

FUROSEMIDE , THIAZIDES & NSAIDs : A FEW FACTS❗️


⚜Furosemide is a loop diuretic

⚜It interferes with the concentrating capacity of the loop of Henle.

⚜It is effective in patients with renal dysfunction, whereas the thiazides are NOT.

⚜It potentiates the nephrotoxic effects of cephalosporins and the ototoxic effects of aminoglycosides.

⚜NSAIDs inhibit renal prostaglandin, causing sodium to be retained, which reduces the diuresis caused by furosemide.

⚜ Furosemide is a venous and arteriolar dilator and thus reduces both preload and afterload in a time frame just before the period of onset of a significant diuresis.



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